Modulation of venlafaxine hydrochloride release from press coated matrix tablet
نویسندگان
چکیده
منابع مشابه
Modulation of Venlafaxine Hydrochloride Release from Press Coated Matrix Tablet
The aim of present study was to prepare novel modified release press coated tablets of venlafaxine hydrochloride. Hydroxypropylmethylcellulose K4M and hydroxypropylmethylcellulose K100M were used as release modifier in core and coat, respectively. A 3(2) full factorial design was adopted in the optimization study. The drug to polymer ratio in core and coat were chosen as independent variables. ...
متن کاملDesign and Evaluation of Extended release tablet of Venlafaxine Hydrochloride using Compression coating method
Venlafaxine Hcl is an anti-depressant drug which is used in depression. The aim of present investigation was to prepare an ER tablet of Venlafaxine Hcl with similar dissolution profile matching to Effexor ER. An immediate release core tablet of 100mg was prepared and it was compression coated using HPMC matrix system. HPMC of three viscosity grades i.e., K4M, K15M, K100M and different concentra...
متن کاملFormulation and evaluation of bilayer tablet for bimodal release of venlafaxine hydrochloride
The aim of the present research was to develop a bilayer tablet of venlafaxine hydrochloride for bimodal drug release. In the present investigation authors have tried to explore fenugreek mucilage (FNM) for bioadhesive sustained release layer. The attempt has been made to combine FNM with well studied bioadhesive polymers like hydroxy propyl methyl cellulose (HPMC), Carbopol, and Xanthan Gum. T...
متن کاملFormulation Development of Venlafaxine Hydrochloride Extended Release Tablet and Invitro Characterizations
Venlafaxine is a unique antidepressant that differs structurally from other currently available antidepressants. Short biological half life, low bioavailabilty and frequent administration of drug led rational for development of extended release formulation of Venlafaxine that releases the drug and maintian the plasma drug concentration for more than 12h.Polymers like Hydroxy propyl methyl cellu...
متن کاملFormulation and Release Behaviour of Sustained Release Ambroxol Hydrochloride HPMC Matrix Tablet
Monolithic matrix tablets of ambroxol hydrochloride were formulated as sustained release tablets employing hydroxypropyl methylcellulose polymer, and the sustained release behaviour of the fabricated tablets was investigated. Sustained release matrix tablets containing 75 mg ambroxol hydrochloride were developed using different drug polymer ratios of hydroxypropyl methylcellulose. Tablets were ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Indian Journal of Pharmaceutical Sciences
سال: 2008
ISSN: 0250-474X
DOI: 10.4103/0250-474x.42974